Kidney Transplant: Surgery, Purpose, Procedure & Recovery
By: Dr. Sunil R
Senior Consultant - Nephrology & Transplant Physician
Posted on April 20, 2025
A kidney transplant is a life-saving procedure for individuals with end-stage kidney disease or severe kidney failure. It involves replacing a failing kidney with a healthy one from a donor. Unlike dialysis, a transplant allows for an improved quality of life and better long-term health outcomes. However, the kidney transplant process requires careful evaluation, surgery, and ongoing post-transplant care.
In this guide, we’ll explore renal transplant surgery, its purpose, procedure, recovery, and what patients can expect before and after the operation.
Understanding Kidney Transplant Surgery
A renal transplant is performed when the kidneys lose their ability to function properly due to chronic diseases such as diabetes, high blood pressure, polycystic kidney disease, or glomerulonephritis. Instead of relying on dialysis, which filters waste and excess fluids from the blood, a kidney transplant restores natural kidney function.
There are two types of kidney transplants:
- Living Donor Transplant – A healthy individual donates one of their kidneys, which is then surgically placed in the recipient. Living donor transplants often have a higher kidney transplant success rate and shorter waiting times.
- Deceased Donor Transplant – A kidney is obtained from a recently deceased donor. Patients on the waiting list may have to wait months or even years for a match.
A successful kidney transplant procedure significantly improves life expectancy and overall well-being. However, it is a major surgery that requires lifelong medical care to prevent complications.
Symptoms of Kidney Failure Leading to Transplant
Patients who require a kidney transplant often experience severe kidney failure symptoms, including:
- Persistent fatigue and weakness
- Swelling in the legs, feet, or face due to fluid retention
- High blood pressure that is difficult to control
- Nausea, vomiting, and loss of appetite
- Difficulty concentrating and mental confusion
- Decreased or dark-coloured urine output
- Shortness of breath and chest pain in severe cases
If you experience any of these symptoms, consult a nephrologist immediately. Early diagnosis can determine whether a renal transplant is the best option for treatment.
What Causes Kidney Failure?
Several medical conditions can lead to kidney failure, making a kidney transplant surgery necessary. Some common causes include:
1. Diabetes
Uncontrolled diabetes can damage the small blood vessels in the kidneys, leading to kidney disease (diabetic nephropathy).
2. High Blood Pressure
Chronic hypertension puts excessive strain on the kidneys, reducing their ability to filter waste efficiently.
3. Polycystic Kidney Disease (PKD)
A genetic condition that causes fluid-filled cysts to develop in the kidneys, eventually leading to kidney failure.
4. Glomerulonephritis
An inflammatory disease that damages the kidney’s filtering units (glomeruli), affecting waste removal from the body.
5. Autoimmune Diseases
Conditions like lupus nephritis can attack kidney tissues, leading to permanent kidney damage.
6. Chronic Infections and Urinary Blockages
Long-term infections or obstructions in the urinary tract can weaken kidney function over time.
If a patient reaches end-stage kidney disease, a kidney transplant may be the best long-term treatment option.
Kidney Transplant Procedure
The kidney transplant process involves several key steps:
1. Pre-Transplant Evaluation
Before undergoing kidney transplant surgery, the patient undergoes detailed medical evaluations, including:
- Blood tests to determine donor compatibility
- Imaging tests (CT scans, ultrasounds)
- Heart and lung function assessments
- Screening for infections and other medical conditions
2. The Surgery
- The donor kidney is placed in the lower abdomen, near the bladder.
- Blood vessels from the kidney are connected to the patient’s blood supply.
- The ureter (urine tube) is linked to the bladder to allow normal urination.
- A kidney transplant surgery typically lasts 3 to 4 hours.
3. Post-Surgical Care
- Patients are monitored closely for complications.
- Medications (immunosuppressants) are prescribed to prevent organ rejection.
- Regular follow-ups ensure the kidney transplant success rate remains high.
Recovery After Kidney Transplant
The post-renal transplant recovery phase is critical. Patients can expect the following:
1. Hospital Stay
- Most patients stay in the hospital for 5 to 10 days after surgery.
- Doctors monitor kidney function, fluid balance, and signs of infection.
2. Medication Management
- Immunosuppressants prevent the body from rejecting the new kidney.
- Additional medications help control blood pressure, cholesterol, and infections.
3. Lifestyle Adjustments
- A balanced diet with low sodium and high protein is essential.
- Regular exercise promotes long-term health without straining the kidneys.
- Hydration helps the new kidney function effectively.
4. Follow-up Appointments
- Frequent check-ups in the first few months
- Ongoing blood tests to monitor kidney health
When to See a Doctor?
If you have chronic kidney disease, consult a specialist if you experience:
- Sudden swelling in the legs, feet, or face
- Extreme fatigue or confusion
- Persistent high blood pressure despite medication
- Frequent infections or urinary issues
- Severe nausea, vomiting, or loss of appetite
For those in Bangalore, please visit SPARSH, a leading Nephrology Hospital in Bangalore. Here, you can consult some of the best nephrologists in Bangalore who will ensure you receive expert medical care.
Conclusion
A kidney transplant is a life-changing procedure that restores normal kidney function, eliminating the need for dialysis. While it requires lifelong medication and regular monitoring, most patients regain a high quality of life after surgery. If you or a loved one is considering a renal transplant, consult a specialist to explore your options and ensure a smooth kidney transplant process.